Au‐Yeung 2014.
Methods | Study design: randomised controlled cross‐over trial Number of dropouts: none Number of adverse effects: not described Deaths: none ITT: yes |
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Participants | Country: China Sample size: 10 participants; mean age (SD) 63 (6) years; mean UE‐FM (SD) 58 (8) Inclusion criteria: not explicitly stated; participants were recruited from a convenience sample from two patient self help groups for stroke; participants were < 80 years of age; had a single stroke more than a year prior to enrolment and had weakness in the affected upper limb and could perform a pincer grip with the index finger Exclusion criteria: not explicitly stated, but people excluded were either illiterate in Chinese, had a history of other neurologic disorders, metal in the head, musculoskeletal pathologies affecting movements in the upper limbs, had aphasia or < 18 points on the MMSE |
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Interventions | Each participant underwent all of the following conditions:
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Outcomes | Outcomes were measured at baseline and at the end of intervention period Primary outcome measures:
Secondary outcome measures:
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Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Quote: "The sequence was determined in advance for each subject by drawing lots from an envelope" |
Allocation concealment (selection bias) | Unclear risk | Quote: "The sequence was determined in advance for each subject by drawing lots from an envelope" |
Blinding of participants and personnel (performance bias) Subjective outcome measures | Unclear risk | Participants were blinded, but personnel were not. Quote: "It was the third investigator (C.Y.) who set the tDCS parameters for both channels and operated the machine behind the subject throughout the experimental procedure" |
Blinding of participants and personnel (performance bias) Objective outcome measures | Low risk | Participants were blinded, but personnel were not. Quote: "It was the third investigator (C.Y.) who set the tDCS parameters for both channels and operated the machine behind the subject throughout the experimental procedure" |
Blinding of outcome assessment (detection bias) Subjective outcome measures | Low risk | Outcome assessors were blinded. Quote: "Two other investigators (J.W. and E.C.) who were blinded to the allocated tDCS conditions then assessed the baseline motor status of the subjects’ paretic upper limb" |
Blinding of outcome assessment (detection bias) Objective outcome measures | Low risk | Outcome assessors were blinded. Quote: "Two other investigators (J.W. and E.C.) who were blinded to the allocated tDCS conditions then assessed the baseline motor status of the subjects’ paretic upper limb" |
Incomplete outcome data (attrition bias) Subjective outcome measures | Unclear risk | All participants apparently completed the study. No treatment withdrawals, no losses to follow‐up, no trial group changes and no major adverse events were stated |
Incomplete outcome data (attrition bias) Objective outcome measures | Unclear risk | All participants apparently completed the study. No treatment withdrawals, no losses to follow‐up, no trial group changes and no major adverse events were stated |
Selective reporting (reporting bias) | Unclear risk | All outcomes reported in the methods section reported |