Fregni 2005a.

Methods	Study design: randomised double‐blind sham‐controlled cross‐over trial Dropouts: none Adverse effects: none Deaths: none ITT: yes
Participants	Country: not clearly stated Number of participants: 6 participants with chronic stroke neuroimaging‐proofed diagnosis; all were right‐handed and all had their strokes at least 12 months before the study Age: (mean ± SD) 53.7 ± 16.6 years Gender: 4 women (66%) Type of stroke: not stated Time poststroke: 27.1 months (range 12 to 72 months) Severity: motor strength (mean ± SD) 4.18 ± 0.37; ASS (mean ± SD) 0.83 ± 0.75 Inclusion criteria: not clearly stated Exclusion criteria: not clearly stated, but the authors referred to Hummel 2005, where the exclusion criteria were as follows: severe depression, history of severe alcohol or drug abuse, severe language disturbances, particularly of a receptive nature, or serious cognitive deficits (MMSE < 23/30 points)
Interventions	Characteristics: each participant underwent 3 different conditions for 20 minutes, separated by at least 48 hours of rest A‐tDCS of the lesioned hemisphere's M1 (1 mA). C‐tDCS of the non‐lesioned hemisphere's M1 (1 mA). Sham tDCS (electrode montage not stated by the authors).
Outcomes	Outcomes used: duration of JTT in seconds Time point of measurement: at baseline after familiarisation session, during stimulation and directly after stimulation
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not described
Allocation concealment (selection bias)	Unclear risk	Not described
Blinding of participants and personnel (performance bias) Subjective outcome measures	Low risk	There were no subjective outcome measures
Blinding of participants and personnel (performance bias) Objective outcome measures	Low risk	Participants were blinded; blinding of personnel was not described
Blinding of outcome assessment (detection bias) Subjective outcome measures	Low risk	There were no subjective outcome measures
Blinding of outcome assessment (detection bias) Objective outcome measures	Low risk	Outcome assessor was blinded; quote: "A blinded neuropsychologist—instructed not to communicate with the patient during the task—evaluated patients’ performance"
Incomplete outcome data (attrition bias) Subjective outcome measures	Low risk	There were no subjective outcome measures
Incomplete outcome data (attrition bias) Objective outcome measures	Low risk	All participants apparently completed the study. No treatment withdrawals, no losses to follow‐up, no trial group changes and no major adverse events were stated
Selective reporting (reporting bias)	Unclear risk	All outcomes reported in the methods section reported