Lee 2014.
Methods | Method: RCT Number of dropouts: 5 (3 out of 42 in the experimental groups (7%) and 2 out of 22 in the control group (9%)) Number of adverse effects: no major adverse events Deaths: none ITT: no |
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Participants | Country: Republic of Korea Sample size: 59 people with stroke (39 in the experimental groups and 20 in the control group) Inclusion criteria: unilateral hemiparesis caused by stroke; first stroke within 1 month prior to enrolment; shoulder motor strength Medical Research Council grade ≤ 2 Exclusion criteria: contraindications to brain stimulation; previous history of brain neurosurgery or epilepsy; metallic implants in the brain; severe cognitive impairment; aphasia interfering with understanding study instructions; poor sitting balance; impaired vision; hemispatial neglect |
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Interventions | 3 arms
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Outcomes | Outcomes were measured at baseline and at the end of intervention period
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Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Quote: "All of the enrolled patients were randomly assigned to 1 of 3 groups using a table of random numbers" |
Allocation concealment (selection bias) | Unclear risk | Not described by the authors |
Blinding of participants and personnel (performance bias) Subjective outcome measures | Low risk | Participants and personnel providing the base treatment were blinded |
Blinding of participants and personnel (performance bias) Objective outcome measures | Low risk | Participants and personnel providing the base treatment were blinded |
Blinding of outcome assessment (detection bias) Subjective outcome measures | Low risk | Quote: "All evaluations were performed before and immediately after treatment by a single experienced occupational therapist who was not aware of the treatment allocation" |
Blinding of outcome assessment (detection bias) Objective outcome measures | Low risk | Quote: "All evaluations were performed before and immediately after treatment by a single experienced occupational therapist who was not aware of the treatment allocation" |
Incomplete outcome data (attrition bias) Subjective outcome measures | High risk | 3 participants out of 42 (7%) in the experimental groups and 2 out of 22 (9%) were lost to follow‐up and excluded from the analysis. 2 out of the 3 losses to follow‐up in the experimental group dropped out due to "medical problem(s)" |
Incomplete outcome data (attrition bias) Objective outcome measures | High risk | 3 participants out of 42 (7%) in the experimental groups and 2 out of 22 (9%) were lost to follow‐up and excluded from the analysis. 2 out of the 3 losses to follow‐up in the experimental group dropped out due to "medical problem(s)" |
Selective reporting (reporting bias) | Unclear risk | All outcomes listed in the methods section reported |