Wang 2014.
Methods | Study design: RCT Number of dropouts: not stated Number of adverse effects: 3 (mild tingling) Deaths: none ITT: unclear |
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Participants | Country: USA Sample size: 9 participants Inclusion criteria: aged between 18 and 90 years; first time clinical ischaemic or haemorrhagic stroke, radiologically confirmed; > 20° wrist extension and > 10° finger extension (all fingers); time since stroke more than 1 month prior to study enrolment Exclusion criteria: significant prestroke disability; advanced or terminal disease; substantial decrease in alertness, language reception or attention interfering with understanding instructions; contraindications to TMS; history of alcohol/drug abuse; participation in another study targeting stroke recovery; use of neuropsychotropic drugs (monoamine oxidase‐inhibitors); epilepsy; marked agitation/anxiety; having already received MP or tDCS treatment; pregnancy |
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Interventions | 3 arms
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Outcomes | Outcomes were measured at baseline, immediately after the intervention and 30 minutes after the end of intervention
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Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Quote: "Subjects were randomly assigned to 1 of 3 groups" |
Allocation concealment (selection bias) | Unclear risk | Not described by the authors |
Blinding of participants and personnel (performance bias) Subjective outcome measures | Low risk | There were no subjective outcome measures |
Blinding of participants and personnel (performance bias) Objective outcome measures | Low risk | Participants were blinded; blinding of personnel not described, however the review authors judge that the outcome measurement is not likely to be influenced by lack of blinding |
Blinding of outcome assessment (detection bias) Subjective outcome measures | Low risk | There were no subjective outcome measures |
Blinding of outcome assessment (detection bias) Objective outcome measures | Low risk | Quote: "A blinded rater measured safety, hand function, and cortical excitability before and after treatment" |
Incomplete outcome data (attrition bias) Subjective outcome measures | Low risk | There were no subjective outcome measures |
Incomplete outcome data (attrition bias) Objective outcome measures | Unclear risk | All participants apparently completed the study. No treatment withdrawals, no losses to follow‐up, no trial group changes and no major adverse events were stated |
Selective reporting (reporting bias) | Unclear risk | All outcomes listed in the methods section reported |