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. 2016 Mar 21;2016(3):CD009645. doi: 10.1002/14651858.CD009645.pub3

NCT01014897.

Trial name or title tDCS in chronic stroke recovery—pilot
Methods Double‐blind randomised sham‐controlled cross‐over trial
Participants 45 people between 18 and 80 years of age with single symptomatic stroke more than 3 months ago with hand/arm weakness and ability to perform required tests and provide consent; Modified Ashworth scale < 3; ROM functional at shoulder, elbow, wrist and hand
Exclusion criteria: more than 1 symptomatic stroke in MCA territory or bilateral involvement; severe medical or psychiatric conditions, drug abuse, seizure disorder; pregnancy/breast‐feeding; SAH, lobar haemorrhage; people who cannot have tDCS (prior head surgery, pacemakers, metallic implants in the head, etc); people taking antiadrenergic medications
Interventions Experimental: subcortical: subcortical stroke participants will receive tDCS stimulation and sham in random order; tDCS and sham will be applied in random order during standardised occupational therapy
Experimental: cortical: participants will receive active and sham tDCS in random order; tDCS and sham will be applied in random order during standardised occupational therapy
Outcomes Primary outcome measures: WMFT at baseline and after the end of the intervention period; UE‐FM at baseline and after the end of the intervention period
Secondary outcome measures: adverse events during the intervention period
Starting date April 2009
Contact information Timea Hodics, MD Timea.Hodics@UTSouthwestern.edu
Notes