NCT01207336.

Trial name or title	Effect of combined anodal tDCS and peripheral nerve stimulation on motor recovery in acute stroke
Methods	Double‐blind RCT (parallel assignment)
Participants	20 people 35 to 85 years of age with first‐ever ischaemic stroke within 5 to 30 days; paresis of the arm/hand with NIHSS < 15 Exclusion criteria: pregnancy, psychiatric history, history of substance abuse or severe depression, severe language disturbances,  patients with increased intracranial pressure or serious cardiac disease, patients with contraindication to TMS
Interventions	Experimental: 1 session of A‐tDCS (1.2 mA for 13 minutes) to the ipsilesional primary motor cortex (M1) combined with peripheral radial nerve electrical stimulation (rEPNS) to the paretic hand repeated on 5 successive days, rEPNS (at radial nerve 5 Hz), 0.7* motor threshold Sham: the same rEPNS regimen as in the experimental group but combined with sham tDCS
Outcomes	Primary outcome measures: Jebsen Taylor test at 5, 15 and 30 days Secondary outcome measures: grip and wrist force at 5, 15 and 30 days; Nine‐Hole Peg Test at 5, 15 and 30 days; cortical excitability of ipsilesional M1 (as measured by TMS) at 5, 15 and 30 days
Starting date	September 2010
Contact information	Marion Simonetta‐Moreau, MD, PhD simonetta.m@chu‐toulouse.fr
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