NCT01503073.

Trial name or title	Noninvasive brain stimulation for stroke improvement
Methods	Double‐blind RCT cross‐over trial
Participants	200 persons 18 to 90 years of age with acute or chronic stroke (and with a slight deficit at least) Exclusion criteria: epilepsy, contraindication to tDCS and/or to fMRI, inability to understand/complete behavioural tasks, history of substance abuse, major health condition, presence of pacemaker, pregnancy
Interventions	Active comparator: tDCS Sham comparator: sham tDCS
Outcomes	Primary outcome measures: change in function before/after tDCS, any brain function impaired by stroke Secondary outcome measures: change in neuroimaging and neurophysiological outcome measures before/after tDCS: (1) noninvasive neuroimaging: brain activity studied by means of fMRI, (2) noninvasive neurophysiological measure: TMS, EEG, evoked potentials, EMG Time points of their measurement: before intervention, immediately after intervention, 10, 20, 30, 40, 50, 60 minutes after intervention; long‐term after intervention: 1, 2, 3 and 4 weeks and 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 and 12 months after the end of the intervention period
Starting date	January 2008
Contact information	Yves Vandermeeren, MD, PhD, yves.vandermeeren@uclouvain.be
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