NCT01519843.

Trial name or title	Post‐stroke procedural learning: from neural substrates to therapeutic modulation by non‐invasive brain stimulation
Methods	Double‐blind randomised controlled cross‐over trial
Participants	200 people 18 to 95 years of age with chronic stroke with an at least slight deficit Exclusion criteria: epilepsy, contraindication to tDCS and/or to fMRI, inability to understand/complete behavioural tasks, history of substance abuse, major health condition, presence of pacemaker, pregnancy
Interventions	Active comparator: tDCS Placebo comparator: sham tDCS
Outcomes	Primary outcome measures: motor learning improvement with tDCS from baseline to 4 weeks after the end of the intervention period as measured by a motor skill learning task and by Purdue Pegboard, hand dynamometer, pinch dynamometer, 9‐HPT Secondary outcome measures: neuroimaging before motor learning task, during motor learning and after (immediately, 30 minutes, 60 minutes) motor learning; neurophysiological outcome measure (of brain excitability and connectivity with TMS (single and paired pulse)) 5 minutes before motor learning, just at the end of motor learning, after 30 minutes of motor learning, after 60 minutes of motor learning and at 1, 2, 3, and 4 weeks after the day of intervention
Starting date	September 2010
Contact information	Yves Vandermeeren, MD, PhD, yves.vandermeeren@uclouvain.be
Notes