NCT01897025.

Trial name or title	Combined transcranial direct current stimulation and motor imagery‐based robotic arm training for stroke rehabilitation ‐ a feasibility study
Methods	RCT with parallel‐group design
Participants	Estimated enrolment: 32 Inclusion criteria: first‐ever stroke more than 9 months prior to study enrolment; upper extremity impairment of 11 to 45 on the Fugl‐Meyer assessment scale Exclusion criteria: epilepsy; neglect; cognitive impairment; other neurological or psychiatric diseases; severe arm pain; spasticity score > 2 MAS in shoulder/elbow joint; contraindications to TMS or tDCS; grip strength < 10 kg as measured by dynamometer; participation in other interventions or trials targeting motor recovery
Interventions	2 arms A‐tDCS with the anode placed over M1 of the affected hemisphere and the cathode placed over M1 of the unaffected hemisphere (1 mA for 20 minutes) followed by MI‐BCI training with the MIT‐Manus for 40 minutes (10 sessions over 2 weeks) Sham tDCS with the anode placed over M1 of the affected hemisphere and the cathode placed over M1 of the unaffected hemisphere (1 mA for 30 seconds) followed by MI‐BCI training with the MIT‐Manus for 40 minutes (10 sessions over 2 weeks)
Outcomes	Outcomes will be recorded at baseline, at the end of intervention period and 4 weeks after the end of intervention period Primary outcome measure UE‐FM Secondary outcome measures Resting Motor Threshold of M1 of the affected hemisphere Grip strength BBT MRI parameters
Starting date	January 2011
Contact information	Effie Chew, MD National University Hospital Singapore, Singapore, 119074
Notes