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. 2016 Mar 21;2016(3):CD009645. doi: 10.1002/14651858.CD009645.pub3

NCT01969097.

Trial name or title Efficacy basics of bihemispheric motorcortex stimulation after stroke
Methods RCT with parallel‐group design
Participants Estimated enrolment: 50
Inclusion criteria: aged between 18 and 80 years; chronic stroke (> 6 months after stroke)
Exclusion criteria: more than 1 stroke; severe alcohol disease or drug abuse; severe psychiatric disease like depression or psychosis; severe cognitive deficits; severe untreated medical conditions; other neurologic diseases; severe microangiopathy; pregnancy
Interventions 3 arms
  1. Dual‐tDCS plus motor training (25 minutes/day) for 5 days

  2. A‐tDCS plus motor training (25 minutes/day) for 5 days

  3. Sham tDCS plus motor training (25 minutes/day) for 5 days

Outcomes Outcomes will be recorded at baseline and at the end of intervention period
Primary outcome measures
  1. Change in motor function of the affected upper extremity after the end of intervention period

  2. Change in motor function of the affected upper extremity at 3‐months follow‐up


Secondary outcome measures
  1. Motor function of the affected upper extremity after the end of intervention period

  2. Motor function of the affected upper extremity at 3‐months follow‐up

  3. fMRI at the end of intervention period and at 3‐months follow‐up

  4. DTI at the end of intervention period and at 3‐months follow‐up

  5. TMS at the end of intervention period

Starting date May 2012
Contact information Robert Lindenberg, M.D.
Charite Universitätsmedizin Berlin
Berlin, Germany, 10117
Notes