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. 2016 Mar 21;2016(3):CD009645. doi: 10.1002/14651858.CD009645.pub3

NCT02080286.

Trial name or title Boosting the therapeutic benefits of prism adaptation by combining it with tDCS
Methods Randomised cross‐over trial
Participants Estimated enrolment: 40
Inclusion criteria: aged 18 to 85 years; right‐hemispheric stroke at least 1 month prior to enrolment;diagnosis of neglect confirmed by the Behavioural Inattention Test (BIT)
Exclusion criteria: adequate understanding of English, sufficient to give informed consent; limited verbal communication in the form of dysphasia; history of drug abuse; history of dementia or other psychiatric conditions
Interventions 3 arms
  1. A‐tDCS over the left/unaffected M1 (1 mA for 20 minutes) on 5 consecutive daily sessions during prism adaptation therapy

  2. Sham tDCS over the left/unaffected M1 (1 mA for 20 minutes) on 5 consecutive daily sessions during prism adaptation therapy

  3. prism adaptation therapy (20 minutes) on 5 consecutive daily sessions during prism adaptation therapy

Outcomes Primary outcome measures
  1. BIT (at week 0 and at week 8)

  2. Neglect Test Battery (at baseline and at weeks 1, 2, 4 and 8)


Secondary outcome measure:
  1. Changes in brain imaging data (at baseline and at week 5)

Starting date February 2014
Contact information Jacinta O'Shea
FMRIB Centre, John Radcliffe Hospital, University of Oxford
Oxford, United Kingdom, OX3 9DU
Notes