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. 2016 Mar 21;2016(3):CD009645. doi: 10.1002/14651858.CD009645.pub3

NCT02109796.

Trial name or title A controlled, randomised study evaluating the immediate effect of one tDCS session on quadriceps strength in hemiparetic patients
Methods Randomised cross‐over trial
Participants Estimated enrolment: 30
Inclusion criteria: written informed consent; stroke > 6 months prior to enrolment; hemiparesis; ability to walk with or without technical assistance; following rehabilitation program for lower limbs
Exclusion criteria: patient with bilateral brain lesion; cerebellar syndrome; apraxia; aphasia; previous orthopedic surgery in paretic lower limb (< 6 months); usual tDCS contraindications; pregnancy
Interventions No detailed information provided except the following quotation: "We test a new electrode configuration: a anodal stimulation opposite to the cortical representation area of the injured hemisphere and a simultaneous stimulation opposite to the homonyme the cortical representation area of the healthy hemisphere. We hypothesis that one session of tDCS with this electrode configuration allow to improve paretic quadriceps strength in hemiparetic patients after stroke."
Outcomes Outcomes will be recorded at baseline and 2 hours after the end of intervention
Primary outcome measure
  1. Maximum voluntary strength of knee extensors


Secondary outcome measures
  1. Resistive peak torque during passive knee flexion

  2. Angle related to the resistive peak torque generation of the knee extensors

  3. Amplitude of the interpolation twitch

  4. EMG activation of the knee flexors and extensors during the strength evaluations (active and passive)

  5. Functional evaluation of the gait performance and balance

Starting date February 2015
Contact information Roche Nicolas, MD PH
Raymond Poincare Hospital
Garches, France, 92380
Notes