NCT02393651.

Trial name or title	Late LTP‐like plasticity effects of tDCS in subacute stroke patients
Methods	RCT with parallel‐group design
Participants	Estimated enrolment: 48 Inclusion criteria: age 18 to 79 years; single ischaemic stroke, documented by a neurologist; subacute stroke within 1 to 3 weeks poststroke; acute hemiparesis with Fugl‐Meyer Stage < IV Exclusion criteria: absence of MEPs; absence of voluntarily movement (Fugl‐Meyer Stage < III); head injury or metal in the head; history of cranial irradiation; history of epilepsy; pacemaker; anticonvulsant or neuroleptic medication; substance abuse; inability to understand instructions history of psychiatric disorders
Interventions	2 arms Dual‐tDCS plus motor training of the affected upper extremity Sham tDCS plus motor training of the affected upper extremity
Outcomes	Primary outcome measure Change in UE‐FM (at 1 week, 2 weeks; 4 weeks and 12 weeks) Secondary outcome measures ARAT (at 1 week, 2 weeks; 4 weeks and 12 weeks) Hand grip strength (at 1 week, 2 weeks; 4 weeks and 12 weeks) 10MWT (at 1 week, 2 weeks; 4 weeks and 12 weeks) EuroQoL‐5D (at 12 weeks) BI (at 1 week, 2 weeks; 4 weeks and 12 weeks) HADS (at 4 and 12 weeks) MoCA (at 4 and 12 weeks) Wong‐Baker FACES Pain Rating Scale (every stimulation session)
Starting date	March 2015
Contact information	Rick van der Vliet, MSc Rijndam Rotterdam, Zuid‐Holland, Netherlands, 3015LJ
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