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. 2016 Mar 21;2016(3):CD009645. doi: 10.1002/14651858.CD009645.pub3

NCT02401724.

Trial name or title A randomised trial of non‐invasive brain stimulation (NIBS) in stroke survivors
Methods RCT with parallel‐group design
Participants Estimated enrolment: 60
Inclusion criteria: aged between 18 and 90 years; ischaemic stroke affecting right hemisphere, radiologically confirmed; persistent neglect > 1 months after stroke, confirmed by BIT; prestroke functional independence (mRS 0 to 2)
Exclusion criteria: patients who do not understand English; bilateral infarcts, radiologically confirmed; MoCA < 26; other neurological diseases; significant morbidity; alcohol excess; exclusion criteria for tDCS
Interventions 4 arms
  1. Training exercises (lifting rods)

  2. Active tDCS over the left/undamaged hemisphere (1 mA for 15 minutes) for 10 sessions in 3 weeks

  3. Training exercises (lifting rods) plus active tDCS over the left/undamaged hemisphere (1 mA for 15 minutes) for 10 sessions in 3 weeks

  4. Control training (reaching rods with the unaffected hand)

Outcomes Primary outcome measure
  1. Change in BIT (at 6 months after the end of intervention)


Secondary outcome measures:
  1. Compliance as measured by adherence to task instructions (at baseline, at 3 weeks and at 6 months)

  2. Retention numbers (at baseline, at 3 weeks and at 6 months)

Starting date March 2015
Contact information Monika Harvey, BSc (Hons), MSc, PhD
NHS Greater Glasgow and Clyde
Notes