1 Function (all scores/instruments): short term (up to 3 months follow‐up) |
4 |
162 |
Std. Mean Difference (IV, Random, 95% CI) |
0.26 [‐0.19, 0.71] |
1.1 Rotator cuff tear (surgical repair) |
0 |
0 |
Std. Mean Difference (IV, Random, 95% CI) |
0.0 [0.0, 0.0] |
1.2 Shoulder impingement syndrome (surgery) |
1 |
40 |
Std. Mean Difference (IV, Random, 95% CI) |
0.62 [‐0.02, 1.25] |
1.3 Elbow epicondylitis |
2 |
68 |
Std. Mean Difference (IV, Random, 95% CI) |
0.41 [‐0.08, 0.89] |
1.4 ACL reconstruction (patellar tendon graft donor site) |
0 |
0 |
Std. Mean Difference (IV, Random, 95% CI) |
0.0 [0.0, 0.0] |
1.5 ACL reconstruction |
0 |
0 |
Std. Mean Difference (IV, Random, 95% CI) |
0.0 [0.0, 0.0] |
1.6 Patellar tendinopathy |
0 |
0 |
Std. Mean Difference (IV, Random, 95% CI) |
0.0 [0.0, 0.0] |
1.7 Achilles tendinopathy |
1 |
54 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.30 [‐0.84, 0.24] |
1.8 Achilles tendon rupture (surgical repair) |
0 |
0 |
Std. Mean Difference (IV, Random, 95% CI) |
0.0 [0.0, 0.0] |
2 Function (all scores/instruments): medium term (over 3 months, under 1 year follow‐up) |
5 |
151 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.09 [‐0.56, 0.39] |
2.1 Rotator cuff tear (surgical repair) |
0 |
0 |
Std. Mean Difference (IV, Random, 95% CI) |
0.0 [0.0, 0.0] |
2.2 Shoulder impingement syndrome (surgery) |
0 |
0 |
Std. Mean Difference (IV, Random, 95% CI) |
0.0 [0.0, 0.0] |
2.3 Elbow epicondylitis |
1 |
27 |
Std. Mean Difference (IV, Random, 95% CI) |
0.74 [‐0.05, 1.52] |
2.4 ACL reconstruction (patellar tendon graft donor site) |
1 |
25 |
Std. Mean Difference (IV, Random, 95% CI) |
0.04 [‐0.76, 0.84] |
2.5 ACL reconstruction |
0 |
0 |
Std. Mean Difference (IV, Random, 95% CI) |
0.0 [0.0, 0.0] |
2.6 Patellar tendinopathy |
1 |
17 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.93 [‐1.95, 0.09] |
2.7 Achilles tendinopathy |
1 |
54 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.04 [‐0.57, 0.49] |
2.8 Achilles tendon rupture (surgical repair) |
1 |
28 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.46 [‐1.21, 0.29] |
3 Functional (all scores/instruments): long term (1 year or more follow‐up) |
10 |
484 |
Std. Mean Difference (IV, Random, 95% CI) |
0.25 [‐0.07, 0.57] |
3.1 Rotator cuff tear (surgical repair) |
6 |
324 |
Std. Mean Difference (IV, Random, 95% CI) |
0.13 [‐0.24, 0.51] |
3.2 Shoulder impingement syndrome (surgery) |
0 |
0 |
Std. Mean Difference (IV, Random, 95% CI) |
0.0 [0.0, 0.0] |
3.3 Elbow epicondylitis |
0 |
0 |
Std. Mean Difference (IV, Random, 95% CI) |
0.0 [0.0, 0.0] |
3.4 ACL reconstruction (patellar tendon graft donor site) |
1 |
40 |
Std. Mean Difference (IV, Random, 95% CI) |
1.53 [0.82, 2.24] |
3.5 ACL reconstruction |
1 |
40 |
Std. Mean Difference (IV, Random, 95% CI) |
0.31 [‐0.31, 0.94] |
3.6 Patellar tendinopathy |
0 |
0 |
Std. Mean Difference (IV, Random, 95% CI) |
0.0 [0.0, 0.0] |
3.7 Achilles tendinopathy |
1 |
54 |
Std. Mean Difference (IV, Random, 95% CI) |
0.03 [‐0.51, 0.56] |
3.8 Achilles tendon rupture (surgical repair) |
1 |
26 |
Std. Mean Difference (IV, Random, 95% CI) |
0.08 [‐0.69, 0.85] |
4 Pain (VAS: 0 to 10: worst pain): short term (up to 3 months follow‐up) |
4 |
175 |
Mean Difference (IV, Fixed, 95% CI) |
‐0.95 [‐1.41, ‐0.48] |
4.1 Rotator cuff tears (surgical repair) |
2 |
107 |
Mean Difference (IV, Fixed, 95% CI) |
‐0.69 [‐1.64, 0.25] |
4.2 Shoulder impingement syndrome (surgery) |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
‐1.4 [‐2.36, ‐0.44] |
4.3 Elbow epicondylitis |
1 |
28 |
Mean Difference (IV, Fixed, 95% CI) |
‐0.86 [‐1.51, ‐0.21] |
4.4 ACL reconstruction (patellar tendon graft donor site) |
0 |
0 |
Mean Difference (IV, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
4.5 ACL reconstruction |
0 |
0 |
Mean Difference (IV, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
4.6 Patellar tendinopathy |
0 |
0 |
Mean Difference (IV, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
4.7 Achilles tendinopathy |
0 |
0 |
Mean Difference (IV, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
4.8 Achilles tendon rupture (surgical repair) |
0 |
0 |
Mean Difference (IV, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
5 Pain (VAS: 0 to 10: worst pain): medium term (over 3 months, under 1 year follow‐up) |
2 |
|
Mean Difference (IV, Fixed, 95% CI) |
Subtotals only |
5.1 Rotator cuff tear (surgical repair) |
0 |
0 |
Mean Difference (IV, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
5.2 Shoulder impingement syndrome (surgery) |
0 |
0 |
Mean Difference (IV, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
5.3 Elbow epicondylitis |
1 |
27 |
Mean Difference (IV, Fixed, 95% CI) |
‐0.75 [‐1.57, 0.07] |
5.4 ACL reconstruction (patellar tendon graft donor site) |
0 |
0 |
Mean Difference (IV, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
5.5 ACL reconstruction |
0 |
0 |
Mean Difference (IV, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
5.6 Patellar tendinopathy |
1 |
20 |
Mean Difference (IV, Fixed, 95% CI) |
1.4 [0.32, 2.48] |
5.7 Achilles tendinopathy |
0 |
0 |
Mean Difference (IV, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
5.8 Achilles tendon rupture (surgical repair) |
0 |
0 |
Mean Difference (IV, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
6 Pain (VAS: 0 to 10: worst pain): long term (1 year or more follow‐up) |
2 |
|
Mean Difference (IV, Fixed, 95% CI) |
Subtotals only |
6.1 Rotator cuff tear (surgical repair) |
2 |
81 |
Mean Difference (IV, Fixed, 95% CI) |
‐0.29 [‐1.02, 0.44] |
6.2 Shoulder impingement syndrome (surgery) |
0 |
0 |
Mean Difference (IV, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
6.3 Elbow epicondylitis |
0 |
0 |
Mean Difference (IV, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
6.4 ACL reconstruction (patellar tendon graft donor site) |
0 |
0 |
Mean Difference (IV, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
6.5 ACL reconstruction |
0 |
0 |
Mean Difference (IV, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
6.6 Patellar tendinopathy |
0 |
0 |
Mean Difference (IV, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
6.7 Achilles tendinopathy |
0 |
0 |
Mean Difference (IV, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
6.8 Achilles tendon rupture (surgical repair) |
0 |
0 |
Mean Difference (IV, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
7 Adverse effects (any of PRT or placebo application) |
11 |
486 |
Risk Ratio (M‐H, Fixed, 95% CI) |
1.31 [0.48, 3.59] |