ISRCTN95369715.

Trial name or title	Achilles Tendinopathy Management: a randomised controlled trial comparing platelet rich plasma with an eccentric loading programme
Methods	Study design: randomised trial Random sequence generation: not reported Allocation concealment: not reported Masking: not reported
Participants	Location: Target sample size (N): 20 Inclusion criteria: midsubstance Achilles tendinopathy diagnosed clinically through pain on palpation at a level of 2‐6 cm above the tendon insertion and ultrasonography; tendinopathy must cause pain during loading activities and limit those activities; duration of at least 3 months; participants > 18 years old and of either sex Exclusion criteria: tendinopathies secondary to systemic conditions such as rheumatoid arthritis and diabetes; insertional Achilles tendinopathies; pregnancy; previous Achilles rupture or surgery; dislocation or fracture of the lower limb within the preceding 12 months
Interventions	PRP: injected into the Achilles tendinopathy, PRP preparation protocol available Controls or placebo or no intervention (standard care): eccentric loading programme
Outcomes	Primary outcomes: VISA‐ A Secondary outcomes: EQ‐5D and complications Timing of outcomes measurement: at 6, 12, 24, 30, 36 and 52 weeks
Starting date	Main ID: ISRCTN95369715 Date of registration: December 2009 Last refreshed on: February 2010 Date of first enrolment: February 2010 Status: completed
Contact information	Name: Matthew Costa Address: Clifford Bridge Road, Coventry, UK CV2 2DX Telephone: Email: N.K.Bains@warwick.ac.uk Affiliation: Warwick Medical School, Clinical Sciences Research Institute
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