Comparison 1. Valacyclovir versus acyclovir.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Ocular involvement	1		Risk Ratio (M‐H, Random, 95% CI)	Totals not selected
1.1 Conjunctivitis	1		Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
1.2 Punctate keratitis	1		Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
1.3 Dendritic keratitis	1		Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
1.4 Dendritic ulcer	1		Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
1.5 Stromal keratitis	1		Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
1.6 Uveitis	1		Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
1.7 Episcleritis	1		Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
1.8 Elevated intraocular pressure	1		Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
1.9 Persistent ocular lesions	1		Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
2 Pain at week 24 (self‐reported; yes)	1		Risk Ratio (M‐H, Random, 95% CI)	Totals not selected
3 Adverse effects	1		Risk Ratio (M‐H, Random, 95% CI)	Totals not selected
3.1 Vomitting	1		Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
3.2 Eyelid or facial oedema	1		Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
3.3 Rectorrhagia	1		Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
3.4 Kidney stone	1		Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
3.5 Disseminated zoster	1		Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]