Comparison 2. Pharmacological interventions.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Severity	4		Mean Difference (IV, Random, 95% CI)	Totals not selected
1.1 Gabapentin versus placebo	1		Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
1.2 Levodopa versus placebo	1		Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
1.3 Vitamin C versus placebo	1		Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
1.4 Vitamin E versus placebo	1		Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
1.5 Vitamin C & E versus placebo	1		Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
1.6 Ropinirole versus levodopa	1		Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
2 QOL: life satisfaction	1		Mean Difference (IV, Random, 95% CI)	Totals not selected
2.1 Levodopa versus placebo	1		Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
3 QOL: negative feelings & complaints	1		Mean Difference (IV, Random, 95% CI)	Totals not selected
3.1 Levodopa versus placebo	1		Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
4 Quality of sleep	2		Mean Difference (IV, Random, 95% CI)	Totals not selected
4.1 Levodopa versus placebo	1		Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
4.2 Ropinirole versus levodopa	1		Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]