NCT02011191.

Methods	Study design: parallel RCT
Participants	Inclusion criteria: adults and children with ESKD requiring HD or PD for a duration of at least 3 months Exclusion criteria: history of consumption > 300 µg/d of biotin; oral contraceptive therapy containing high amounts of oestrogen; women of childbearing age
Interventions	Treatment group Biotin: 10,000 µg biotin daily for 8 weeks Control group Placebo: sugar pill
Outcomes	Biotin status Change in RLS symptoms
Notes	ClinicalTrials.gov last updated: 12 December 2013 No data available