Nakaya 1990.

Methods	Study design: randomised double‐blind trial Period of study: not reported (published in 1990) Unit of randomisation: participants Unit of analysis: participants
Participants	Hyperlipidaemic participants n = 66 participants
Interventions	Type of interventions: morning vs evening doses of simvastatin M‐DG: 10 mg daily dose of pravastatin after breakfast E‐DG: 10 mg daily dose of pravastatin after dinner Duration of intervention: 12 weeks
Outcomes	Change in lipid levels: TC, HDL‐C and triglycerides levels (mg/dL) Treatment side effects
Notes

E‐DG: evening‐dose group
 HDL‐C: high‐density lipoprotein cholesterol
 TC: total cholesterol