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. 2015 Dec 9;2015(12):CD010143. doi: 10.1002/14651858.CD010143.pub2

Summary of findings 2. Summary of findings table 2: comparison of operation types: late results of needle fasciotomy vs limited fasciectomy for Dupuytren's disease.

Comparison of operation types: late results of needle fasciotomy vs limited fasciectomy for Dupuytren's disease
Patient or population: 93 participants (van Rijssen 2012a)
Settings: single‐centre Dutch study
Intervention: needle fasciotomy
Comparison: limited fasciectomy
Outcomes Illustrative comparative risks* (95% CI) Number of participants
 (studies) Quality of the evidence
 (GRADE) Comments
Assumed risk Corresponding risk
Limited fasciectomy Needle fasciotomy
DASH hand function score at 5 years
Major outcome group 1 (hand function)
(scores between 0 and 100, where 0 represents no impairment in hand function and 100 represents maximum impairment in hand function)
See comment See comment See comment See comment Not studied in van Rijssen 2012a
Patient satisfaction at 5 years
Major outcome group 2 (other PROM)
(scores between "1 (not at all), 10 (excellent)")
Mean satisfaction score in fasciectomy group was 8.3 Mean satisfaction score in fasciotomy group was 2.1 lower than in fasciectomy group 93
 (1 study) ⊕⊕⊝⊝
 Lowa P value < 0.001 as quoted in van Rijssen 2012a
Likelihood of selecting treatment again significantly higher after fasciectomy (P value = 0.008)
Insufficient detail in article to allow calculation of 95% CI (standard deviations not provided)
Major outcome group 3 (early angular outcome)b See comment See comment See comment See comment This major outcome group is not relevant to a late outcome comparison
Recurrence at 5 years
Major outcome group 4 (recurrence)
Defined as reoperation or progressive angular deformity of 20 degrees in a successfully treated joint
209 per 1000 849 per 1000 93
 (1 study) ⊕⊕⊝⊝
 Lowc Progressive angular deformity defined in van Rijssen 2006 as an increase in TPED ≥ 30 degrees. In van Rijssen 2012a, different definitions used (increase of 20 degrees in a successfully treated joint) in other studies of Dupuytren's disease, such as Hurst 2009, acknowledged and applied
P value < 0.001 in van Rijssen 2012a
Relative effect not calculated, as only study available
Recurrence rate influenced by the definition of recurrence used, and by length of follow‐up period
Major outcome group 5 (adverse effects)d see comment see comment see comment see comment Not discussed in van Rijssen 2012a; analysed in van Rijssen 2006
*The basis for the assumed risk (e.g. median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
 CI: Confidence interval; DASH: Disabilities of the Arm, Shoulder and Hand Scale; PROM: Patient‐reported outcome measure; RR: Risk ratio; TPED: Total passive extension deficit.
GRADE Working Group grades of evidence.
 High quality: Further research is very unlikely to change our confidence in the estimate of effect.
 Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
 Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
 Very low quality: We are very uncertain about the estimate.

aQuality of evidence for patient satisfaction at 5 years downgraded from high to low because of significant risks of bias in van Rijssen 2012a, and as the result of imprecision.
 bEarly angular outcomes and adverse effects not considered in this table, as these are relevant to early outcome assessment, and so are included in the previous 'Summary of findings' table.

cQuality of evidence for recurrence at 5 years downgraded from high to low because of significant risks of bias in van Rijssen 2012a, and as the result of imprecision.
 dEarly angular outcomes and adverse effects not considered in this table, as these are relevant to early outcome assessment, and so are included in the previous 'Summary of findings' table.