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. 2015 Dec 9;2015(12):CD010143. doi: 10.1002/14651858.CD010143.pub2

Citron 2003.

Methods Single‐centre UK study
Pseudorandomised controlled clinical trial
Recruitment between 1996 and 2000
Participants 30 participants
24 male:6 female
Mean age (at diagnosis): 67 years for treatment group; 66 years for control group
Inclusion criteria: yes: "Dupuytren’s contracture of a single ray confined to the palm and affecting only the MCPJ, a single cord of Dupuytren’s tissue, no previous surgery for Dupuytren’s disease in that ray, agreement to surgery"
Exclusion criteria: not specified
Interventions Longitudinal incision closed with z‐plasty
vs
Transverse incision
Outcomes
  • Recurrence (reappearance of palpable disease)

    • Lower recurrence in z‐plasty group than in direct closure group (P value < 0.1)

  • MCPJ flexion deformity: preoperative, postoperative

    • No statistical analysis presented

    • Both outcomes measured by 5 different unblinded assessors over the course of the study; outcomes assessed at 2 years postop

  • Complications reported? yes

  • Details: "no complications"

Notes Mean length of follow‐up: 2 years (range 2.0 to 3.5)
Low‐quality evidence, as pseudorandomised and at high risk of bias and imprecision
No funding sources acknowledged; no conflicts of interest declared.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) High risk Alternation rather than randomisation
Allocation concealment (selection bias) High risk Alternation rather than randomisation
Incomplete outcome data (attrition bias) 
 All outcomes Low risk 10% loss to follow‐up but balanced between groups
Selective reporting (reporting bias) Low risk Primary outcomes reported
Other bias Unclear risk Unblinded study with alternation rather than randomisation.
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Surgeon unblinded
Blinding of outcome assessment (detection bias) 
 All outcomes High risk Multiple unblinded assessors throughout study