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. 2013 May 31;2013(5):CD002842. doi: 10.1002/14651858.CD002842.pub2

Sturm 1991

Methods RCT, cross‐over group design
Participants with left brain damage were allocated to 2 comparable groups with respect to age, sex and time post‐onset. Allocation of people to treatment group by random number table. There was a third training group with right brain damaged people. They were trained 'late' in the cross‐over design and their data were excluded from the current analysis
Approach: restore attentional functions by computer training
Participants Germany
Total participants sample: 37; 0 people lost to follow‐up
Treatment group: n = 13; mean age 51.5 ± 9.5 years; 69.2% males; 15 ± 9.7 weeks since onset; hemisphere of lesion: 13 left, 1 non‐stroke participant
Control group: n = 14; mean age 49.6 ± 9.5 years; 71.4% males; 16.4 ± 9.2 weeks since onset; hemisphere of lesion: 14 left, 2 non‐stroke participants No inclusion or exclusion criteria specified, all participants had attentional deficits according to authors
Interventions Treatment: 30 minutes' computer‐based training at clinic, 14 sessions spread over 3 consecutive weeks. Cognitrone and Wiener Determinationsgerat were used as training software Control: no treatment
Outcomes Measured after intervention at 3 weeks, after cross‐over at 6 weeks and at 12 weeks' follow‐up
Several measures, but no definition of primary outcome measure:
  • Wiener Determinationsgerat (hits and false alarms, z‐scores)

  • Cognitrone (hits and false alarms, z‐scores)

  • Wiener Reaktionsgerat (reaction times for visual, auditory and choice subtests, z‐scores)

  • Wiener Vigilanzgerat (hits and false alarms, z‐scores)

  • d2 (hits minus errors, z‐scores)

  • Non‐attentional tasks, such as Raven Standard Progressive Matrices and WAIS subtests

Notes Cognitrone and Wiener Determinationsgerat were used for training, outcome measures based on these tasks were excluded for analysis
Control group was more aphasic and scored significantly lower on WAIS, in the Intelligence structure task and the Ravens than the intervention group
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Use of random number table (personal communication of authors)
Allocation concealment (selection bias) Unclear risk No information
Blinding of participants and personnel (performance bias) All outcomes Unclear risk No information
Blinding of outcome assessment (detection bias) All outcomes Unclear risk No information
Incomplete outcome data (attrition bias) All outcomes Low risk No missing outcome data, but it is noteworthy that 90% of people with right brain damage initially agreed to participate in the study refused to participate when contacted later for starting the training
Selective reporting (reporting bias) Low risk No indication in article, but study protocol not available