Menefee 2011.

Methods	Double‐blinded triple‐arm RCT Randomisation, allocation concealment, NS power, 33 in each group, 80% power to detect 35% difference with 5% type 2 error 2‐Year review
Participants	Inclusion: women ≥ 18 years of age with a POPQ point Ba ≥ 0 Exclusion: NS Concomitant surgery: hysterectomy, colpopexy, posterior repair, continence at surgeon's discretion
Interventions	99 randomised A (32): standard anterior colporrhaphy using midline plication with delayed absorbable suture B (31): vaginal paravaginal repair using free‐hand formed porcine dermis graft (Pelvicol) C (36): vaginal/paravaginal repair using free‐formed polypropylene mesh (M). All graft material was secured to the arcus tendineus fascia pelvis by a Capio device with permanent monofilament suture
Outcomes	Assessed at 2 years Reported the following review outcomes at 2 years Repeat surgery for prolapse Recurrence of prolapse (POPQ Ba stage 2 or greater) Bladder injury (no events) Mesh erosion Objective failure of anterior compartment Sexual function: de novo dyspareunia (data not used, as no denominator reported); PISQ‐12 (median and range) Quality of life: PFIQ (median and range) Operating time Blood transfusion (no events)
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Computer‐generated sequence
Allocation concealment (selection bias)	Low risk	Opaque envelopes
Blinding of participants and personnel (performance bias) All outcomes	Low risk	Double‐blinded
Blinding of outcome assessment (detection bias) All outcomes	Low risk	Double‐blinded
Incomplete outcome data (attrition bias) All outcomes	Low risk	Moderate attrition 1 year: AC 24/32 (75%) ‐ porcine 26/31 (84%), mesh 28/36 (77%)
Selective reporting (reporting bias)	Low risk	Significant outcome data
Other bias	High risk	Study authors reported COI with companies producing product evaluated; funding by Boston Scientific, whose product Capio was being evaluated