Skip to main content
. 2016 Nov 16;2016(11):CD008720. doi: 10.1002/14651858.CD008720.pub2

ISRCTN17078060.

Trial name or title In vitro maturation as part of the treatment of infertility in women with polycystic ovaries. Is priming with hCG favourable? A prospective randomized study.
Methods Prospective open label randomised controlled trial.
Participants 1. Women with polycystic ovaries (PCO) according to Rotterdam criteria (2003)
 2. Referred to the Fertility Clinic, Odense University Hospital
 3. Candidates for IVF‐treatment according to the standards of the Fertility Clinic
Interventions hCG injection vs no injection 36 hours before aspiration of oocytes
Outcomes Primary outcomes:
  1. Maturation rate (number of mature oocytes per number of aspirated oocytes) at 30 and 46 hours

  2. Fertilization rate (number of fertilized oocytes per number of matured oocytes) at 46 and 70 hours


Secondary outcomes:
  1. Number of transferable embryos with normal development on day 2 after fertilization, as a fraction of aspirated, matured and fertilized oocytes in IVF and Intra Cytoplasmatic Sperm Injection (ICSI) groups

  2. Maturation rate in relation to follicle size (46 hours after maturation)

  3. Maturation rate in relation to serum concentrations of various hormones, measured on various cycle days and days of randomisation and aspiration

Starting date 01 April 2006
Contact information Department of Obstetrics and Gynaecology
 Odense University Hospital
 Soendre Boulevard 29
 Odense C
 5000
 Denmark
 +45 6541 1572
Notes Contacted to confirm if data available or published, but no response.