Carson 2009.

Methods	Randomised controlled trial
Participants	Women with diagnosed stage IA‐IIB breast cancer at least 2 years before the start of the study, experiencing hot flashes and currently not receiving chemotherapy or taking hormone replacement therapy Recruited from Duke University Medical Cancer Center Breast Oncology Mean age 54.4 years N = 37
Interventions	• Yoga of Awareness (yoga postures, breathing techniques, meditation, study of pertinent topics, group discussion), 8 weeks, once weekly for 120 minutes • Wait‐list, no treatment for 8 weeks
Outcomes	Fatigue (daily diary) weeks 7‐8 and week 20
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	"Randomization assignments were generated by an individual not involved in the study using a random number table."
Allocation concealment (selection bias)	Low risk	"Assignments were concealed in envelopes that were not opened until patients had completed their baseline assessment."
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	No information on blinding of participants and personnel
Blinding of outcome assessment (detection bias) All outcomes	Low risk	"The research assistant collecting assessment data was kept blind with regard to patient condition assignments." "Diary data was collected via an interactive telephone voice system."
Incomplete outcome data (attrition bias) All outcomes	Low risk	24% dropout in the yoga group and 15% in the control group; intention‐to‐treat analysis
Selective reporting (reporting bias)	Low risk	No protocol available but no hint of selective reporting
Other bias	Low risk	No hint of other bias