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. 2017 Jan 3;2017(1):CD010802. doi: 10.1002/14651858.CD010802.pub2

Kovacic 2013.

Methods Randomised controlled trial using Latin Square randomisations
Participants Women with diagnosed stage I‐II breast cancer receiving multi‐modal therapy (surgery, radiotherapy, chemotherapy)
Recruited from the Institute for Oncology Ljubljana
Mean age not reported
N = 32
Interventions • Yoga in Daily Life® System (yoga postures, breathing techniques, deep relaxation, progressive muscle relaxation, meditation), 1 week, once daily for 45 minutes combined with standard physiotherapy
• Standard physiotherapy
Outcomes Anxiety (Spielberger's State‐Trait Anxiety Inventory) at week 2 and week 5
Notes Duplicate publications separately reported different outcomes of the same trial.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk "The Latin Square randomization method was used in the study. Stratifying factors were type of surgery, severity and stage of breast cancer, and socio‐demographic
 characteristics (age, marital status, employment status, education). Baseline values between experimental and control group regarding stratifying factors were successfully equalized."
"A randomization list was prepared by the independent statistician using the random permuted blocks. This technique has ensured that equal numbers of patients within each stratum were randomized to each intervention (restricted stratified randomization)."
Allocation concealment (selection bias) Low risk No information on allocation concealment
Blinding of participants and personnel (performance bias) 
 All outcomes High risk "[...] patient blinding was impossible [...]"
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk "Outcome measures were obtained by blinded assessors [...]."
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk No information on attrition
Selective reporting (reporting bias) High risk Duplicate publications separately reported different outcomes of the same trial.
Other bias Low risk No hint of other bias