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. 2017 Jan 3;2017(1):CD010802. doi: 10.1002/14651858.CD010802.pub2

Littman 2012.

Methods Randomised controlled trial
Participants Overweight or obese women with diagnosed stage 0‐III breast cancer at least 3 months post treatment (with the exception of antihormonal treatment)
Recruited via oncologist referrals, advertising, announcements, a website and direct mailings to interested women
Mean age 60.6 years
N = 63
Interventions • Viniyoga (yoga postures, breathing techniques, deep relaxation, meditation), 6 months, 1 to 3 times a week for 75 minutes
• Wait‐list, no treatment for 6 months
Outcomes Health‐related quality of life (Functional Assessment of Cancer Therapy ‐ General) at week 48
Fatigue (Functional Assessment of Chronic Illness Therapy ‐ Fatigue) at week 48
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk "Eligible women were block randomized to the intervention or a waitlist control group on age (three strata: 21–49, 50–69, and 70–75 years), stage (two strata: 0/I and II/III), and BMI (two strata: 24–29.9 and ≥30 kg/m2) to assure comparability in the two groups."
Allocation concealment (selection bias) Unclear risk No information on allocation concealment
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk No information on blinding of participants and personnel
Blinding of outcome assessment (detection bias) 
 All outcomes High risk "[...] due to the pilot nature of the study and limited funding, we were unable to blind assessors to group assignment."
Incomplete outcome data (attrition bias) 
 All outcomes Low risk 16% dropout in yoga group and 13% dropout in control group within 12 months; intention‐to‐treat analysis
Selective reporting (reporting bias) Low risk No protocol available but no hint of selective reporting
Other bias Low risk No hint of other bias