Moadel 2007.
Methods | Randomised controlled trial using minimisation | |
Participants | Women with diagnosed stage I‐III breast cancer within the previous 5 years Recruited from a university medical centre and from private clinics Mean age 54.8 years N = 164 |
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Interventions | • Hatha yoga (yoga postures, breathing techniques, meditation), 12 weeks, once weekly for 90 minutes • Wait‐list, no treatment |
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Outcomes | Health‐related quality of life (Functional Assessment of Cancer Therapy ‐ Breast Cancer; Functional Assessment of Chronic Illness Therapy ‐ Spiritual Well‐Being) at week 4, week 12 and week 24 Anxiety (Distressed Mood Index) at week 4, week 12 and week 24 Fatigue (Functional Assessment of Chronic Illness Therapy ‐ Fatigue) at week 4, week 12 and week 24 |
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Notes | Outcomes at week 24 not reported | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | "Random assignment was in a 2:1 ratio to intervention or control after stratification by treatment (chemotherapy or antiestrogen therapy)." "After acquisition of written informed consent and the baseline assessment, patients were randomly assigned to start classes either immediately or in 3 months." |
Allocation concealment (selection bias) | Unclear risk | No information on allocation concealment |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | No information on blinding |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | No information on blinding |
Incomplete outcome data (attrition bias) All outcomes | Low risk | 22% dropout in yoga group and 21% dropout in control group; intention‐to‐treat analysis |
Selective reporting (reporting bias) | Low risk | No protocol available but no hint of selective reporting |
Other bias | Low risk | No hint of other bias |