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. 2011 Sep 7;2011(9):CD002008. doi: 10.1002/14651858.CD002008.pub4

Campbell 2008.

Methods Randomised controlled trial. 
 Duration 12 weeks.
Participants Adults (n = 62) with stage 4 chronic kidney disease, 56 started study, male n = 34, female n = 22, intervention group mean age 69.5 (SD 11.7) years; control mean age 70.9 (SD 11.6) years.
Nutritional status assessed using SGA, intervention group 24% malnourished (SGA B), control group 11% malnourished (SGA B).
50 patients completed the study.
Interventions Dietary counselling to increase energy intake, maintain protein intake and information on appropriate nutritional choices for renal patients (n = 24) versus usual care (generic information on nutrition, n = 26).
Outcomes Dietary intake*, body weight*, nutritional status (SGA), body composition (total body potassium), survival * biochemistry.
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Computer‐generated number sequence.
Allocation concealment (selection bias) Low risk Described as concealed to recruiting officer until after baseline assessment.
Blinding (performance bias and detection bias) 
 Clinical outcomes Unclear risk Not stated.
Blinding (performance bias and detection bias) 
 Functional outcomes Unclear risk Not stated.
Blinding (performance bias and detection bias) 
 Nutritional outcomes Unclear risk Not stated.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk 62 participants randomised in the study: 6 participants did not receive the intervention; 6 were lost to follow; 4 deaths ( all in the intervention group); 2 participants received dialysis.
Selective reporting (reporting bias) Low risk Data on mortality, change in weight and energy intake were used in this review. The data are reported in the paper but the weight data is presented as a mean (SD) at baseline and at 12 weeks and therefore the mean change with SD has been obtained from the authors. The energy intake data reported in kJ/kg, mean change (SD) in kcals obtained from the author.
Other bias Unclear risk Baseline variables stated, groups similar at baseline apart from amounts of malnutrition (see above).