| Methods |
Randomised controlled trial.
Duration 42 days (21 days in hospital and 21 days at home). |
| Participants |
Adults (n = 9, all men, mean age (SD) 62.4 years (5.6 years)) with COPD with FEV1 30 ‐ 50% of predicted and >5% weight loss, mean per cent IBW at study entry 78.5% (SD 9.6%). |
| Interventions |
Individualised diet planned by dietitian to provide 100% of recommended daily intake (n = 4) versus individually planned diet and 1080 kcal of a nutritional supplement (n = 5). |
| Outcomes |
Survival*, weight*, BMI*, TSF*, MAMC*, MUAC*, energy intake*, measures of pulmonary function (FEV1*), measures of immune function. |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
Described as randomised but method not stated. |
| Allocation concealment (selection bias) |
Unclear risk |
Method not stated. |
| Blinding (performance bias and detection bias)
Clinical outcomes |
Unclear risk |
Not discussed. |
| Blinding (performance bias and detection bias)
Functional outcomes |
Unclear risk |
Not discussed. |
| Blinding (performance bias and detection bias)
Nutritional outcomes |
Unclear risk |
Not discussed. |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
No losses occurred during the study. |
| Selective reporting (reporting bias) |
Low risk |
All outcomes reported but not in a format suitable for direct entry into a meta‐analysis. Data in the paper on weight have been used to derive mean change (SD). Information on study quality obtained from authors. |
| Other bias |
Low risk |
Baseline variables given, groups similar at baseline. |
