Jensen 1997.
Methods | Randomised controlled trial. Duration 110 days. | |
Participants | Adults (n = 87, 42 men and 45 women, separated into >75 years and <75 years) post‐surgery (operable cancer colon/rectum (50), diverticulitis (15), ulcer (5) and other (17)). Nutritional status at inclusion was unclear. 28 dropouts (20 dietary advice group and 8 in no advice group). |
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Interventions | Dietary counselling to improve nutritional intake and aiming for a protein intake of 1.5 g/kg using oral nutritional supplements if required (n = 40) versus no nutritional advice (n = 47). | |
Outcomes | Weight *, body composition (DEXA), energy intake*, appetite, fatigue assessments, handgrip strength*, work capacity, respiratory function*, QoL. | |
Notes | Additional data awaited from authors. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | No details of sequence generation reported. Randomisation was stratified. |
Allocation concealment (selection bias) | Low risk | Sealed envelopes. |
Blinding (performance bias and detection bias) Clinical outcomes | Low risk | The paper states that the surgeon was blinded to intervention group. |
Blinding (performance bias and detection bias) Functional outcomes | High risk | Insufficient information in the paper. |
Blinding (performance bias and detection bias) Nutritional outcomes | High risk | Assessment not blinded. |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | 28 dropouts (20 dietary advice group and 8 in no advice group). Reasons for withdrawals not given in paper and not provided by authors on request. |
Selective reporting (reporting bias) | Unclear risk | All specified outcomes reported but not in a format usable for meta analysis, energy intake data presented as kcal/kg and weight change data described in text as mean at baseline and end of follow‐up. Additional data on mean change (SD) for weight and energy intake requested from authors but not provided. |
Other bias | Unclear risk | Baseline variables given, control group (no advice) were significantly older and heavier than the treatment (advice plus supplements if required) group. |