Ollenschlager 1992.

Methods	Randomised controlled trial. Mean duration 25.5 weeks.
Participants	Adults (n = 29, aged 17 ‐ 60 years), undergoing chemotherapy for acute leukaemia who had undesired weight loss >5% or weight 90% below ideal body weight. 2 deaths in the dietary advice group.
Interventions	Daily dietary instruction and modification of diet (n = 15) versus ad libitum intake (n = 16).
Outcomes	Weight*, survival*, number of complete remissions and days temperature >38.5 C, nutrient intake*, subjective well‐being.
Notes	Data given for mean study period. Data on nutrient intake and subjective well‐being only collected for intervention group so not used. Additional data and information obtained from authors.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Described as randomised, method not stated.
Allocation concealment (selection bias)	Unclear risk	Method not stated.
Blinding (performance bias and detection bias) Clinical outcomes	Unclear risk	Not stated.
Blinding (performance bias and detection bias) Functional outcomes	Unclear risk	Not stated.
Blinding (performance bias and detection bias) Nutritional outcomes	Unclear risk	Not stated.
Incomplete outcome data (attrition bias) All outcomes	Low risk	2 deaths in the dietary advice group.
Selective reporting (reporting bias)	High risk	Data given for mean study period. Data on nutrient intake and subjective well‐being only collected for intervention group so not used. Data on weight change presented as % of ideal body weight, mean change (SD) not available from authors and so not included in the review. Additional data on mortality and information on some outcomes obtained from authors.
Other bias	Low risk	Baseline variables given, groups similar at baseline.