Ravasco 2005a.

Methods	Randomised controlled trial. Duration 42 days intervention plus 3 months.
Participants	Adults (n = 111, 66 men and 45 women, mean (SD) age 58 years (15)) with colorectal cancer undergoing radiotherapy. At baseline 42/111 participants were 'malnourished' (identified by PG‐SGA); 15 in Group 1, 14 in Group 2, 13 in Group 3). No participants lost to follow‐up.
Interventions	Individualised dietary counselling to achieve calculated energy and protein requirements (n = 37) versus 2x 200 ml cans of nutritional supplement (n = 37) versus ad libitum food intake (n = 37).
Outcomes	Survival*, weight*, BMI*, energy intake*, protein intake, symptom‐induced morbidity, QoL.
Notes	Data will be used in 2 parts of the review dietary advice versus no advice and dietary advice versus nutritional supplements. Additional data and information obtained from authors.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Computer‐generated random numbers
Allocation concealment (selection bias)	Low risk	Sequentially numbered sealed opaque envelopes.
Blinding (performance bias and detection bias) Clinical outcomes	Unclear risk	Not stated.
Blinding (performance bias and detection bias) Functional outcomes	Unclear risk	Not stated.
Blinding (performance bias and detection bias) Nutritional outcomes	Unclear risk	Not stated.
Incomplete outcome data (attrition bias) All outcomes	Low risk	No participants lost to follow up.
Selective reporting (reporting bias)	Low risk	All specified outcomes reported but in text and figures but not in a format or sufficient detail to make them usable for meta‐analysis. Additional data on mean change (SD) for weight and energy intake obtained from author. Author confirmed that no deaths occurred in the 3‐month study.
Other bias	High risk	Baseline variables not given, not sure if groups similar at baseline.