Sharma 2002.

Methods	Randomised controlled trial. Duration 1 month.
Participants	Adults with renal disease receiving maintenance dialysis (n= 47). All patients had a BMI <20 kg/m2. 7 dropouts (5 in the intervention group and 2 in the control group).
Interventions	Dietary counselling to increase intake but in line with current recommendations for renal disease plus 300 ml of supplement (500 kcals, 15g protein) or home produced blend providing similar kcals and protein (n = 10) versus dietary counselling to increase intake but in line with current recommendations for renal disease (n = 14).
Outcomes	Weight*, biochemistry, energy intake*, supplementation acceptability questionnaire.
Notes	Study is eligible for inclusion on the basis of the intervention however due to the high number of control participants that crossed over to the intervention, data cannot be included without further analysis.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	No details given.
Allocation concealment (selection bias)	Unclear risk	No details given.
Blinding (performance bias and detection bias) Clinical outcomes	Unclear risk	Not mentioned.
Blinding (performance bias and detection bias) Functional outcomes	Unclear risk	Not mentioned.
Blinding (performance bias and detection bias) Nutritional outcomes	Unclear risk	Not mentioned.
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	7 dropouts (5 in the intervention group and 2 in the control group). Reasons not given.
Selective reporting (reporting bias)	Unclear risk	All outcome measures are reported. Data not all in usable format and not available from author, therefore mean change (SD) has been derived by calculation from the data in Table 2.
Other bias	High risk	Baseline data only presented on participants that completed the study (n = 40). 5 patients crossed over from the control to the supplement group.