Wilson 2001.

Methods	Randomised controlled trial. Duration 9 months (6 month treatment and 3 months follow‐up).
Participants	Adults (n = 32, dietary advice and supplement group 39% men, 61% women, mean (SD) age 64 years (10 years); and dietary advice group 14% men and 86 % women, mean (SD) age 58 years (8.6 years)) with hypoalbuminaemia (serum albumin 3.5 ‐ 3.7 g/dL) receiving hemodialysis. An additional group is included with severe hypoalbuminaemia (serum albumin 2.5 to 3.4 g/dL who received intervention according to current practice. 5 participants were not included in the analysis but details of the group allocation is unclear.
Interventions	Dietary counselling to increase energy and protein intakes and 1‐2 cans of supplement (250 calories per serving) (n = 16) versus dietary counselling to increase energy and protein intake (n = 16).
Outcomes	Time to nutritional repletion, number of days spent in hospital*.
Notes	No usable data from this study.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Described as randomised, but method not stated.
Allocation concealment (selection bias)	Unclear risk	Not stated.
Blinding (performance bias and detection bias) Clinical outcomes	Unclear risk	Not stated.
Blinding (performance bias and detection bias) Functional outcomes	Unclear risk	Not stated.
Blinding (performance bias and detection bias) Nutritional outcomes	Unclear risk	Not stated.
Incomplete outcome data (attrition bias) All outcomes	High risk	5 participants were not included in the analysis but details of the group allocation is unclear therefore risk of bias.
Selective reporting (reporting bias)	High risk	The methods section of the paper states that height, weight and weight history and serum albumin are collected at baseline, The results section reports % achieving nutritional repletion defined by improvement in serum albumin and length of hospital stay but no data on weight change. No response received from authors.
Other bias	High risk	Baseline variables given, the dietary counselling and supplement group were significantly older than the dietary group, therefore risk of bias.