NCT00878085

Trial name or title	fMRI and robot‐assisted practice of activities of daily living
Methods	RCT
Participants	Country: USA Participants: estimated enrolment n = 61 Inclusion criteria: age between 30 to 85 years; right‐handedness; unilateral ischaemic stroke in the motor control area with resulting hemiparesis in the arm; time since stroke at least 6 months; residual movement of at least 15° shoulder flexion or adduction and 15° active elbow flexion and extension; no claustrophobia; not depressed; passes the fMRI scanner; being able to understand the instructions and complete the tracking tasks; no history of neurological disorders Exclusion criteria: brainstem stroke; spasticity > 3 at elbow or fingers on Ashworth Scale; visuospatial, language, or attention deficits of a severity that prevents understanding of the task; shoulder pain or joint pain during movements; decline to participate; will not comply with full protocol; pregnant; allergic to Gore‐Tex and conductivity gel
Interventions	Experimental group: robot therapy with ADLs 3 times a week for 4 weeks Control group: occupational therapy 3 times a week for 4 weeks
Outcomes	Outcomes will be collected at baseline, at the end of study, and at follow‐up Primary outcomes: FMA functional hand evaluation (ADL) Jebsen‐Taylor movement time grasp aperture movement smoothness BOLD response (activation) laterality index fractional anisotropy fiber density index secondary outcomes joint range of motion manual muscle test spasticity pain exertion
Starting date	November 2008
Contact information	Michel Torbey, MD; Medical College of Wisconsin
Notes	This study has been completed. No study results posted