NCT01253018

Trial name or title	Evaluation of robot assisted neuro‐rehabilitation (SRT3)
Methods	RCT
Participants	Country: USA Participants: estimated enrolment n = 75 Inclusion criteria: age over 21 years; clinically defined unilateral hemiparetic stroke (radiologically confirmed); adequate language and cognitive function to participate in training, testing, and informed consent; FMA score with a range of 7 to 38 in the study arm; stroke onset at least 6 months for ischaemic and at least 1 year for haemorrhagic stroke Exclusion criteria: seizures or treatment with anticonvulsants in the past 10 years (for transcranial magnetic stimulation testing); any medication known to interfere with brain stimulation; serious complicating medical conditions, contractures, or orthopaedic problems in the study arm limiting the range of motion for study positions; serious visual loss; Botox injection 3 months prior to enrolment; any change in the exercise regimen involving the study arm
Interventions	Experimental group: 12 weeks of robot therapy consisting of a progression through 3 robot modules: wrist, planar, and alternating wrist and planar robot. The progression will be sequential, with 4 weeks of training on each robotic device Control group: 12 weeks of task‐specific practise of functional activities using the hemiparetic arm
Outcomes	Outcomes will be collected at baseline and at the end of study Primary outcomes: FMA Secondary outcomes: motor cortex excitability via transcranial magnetic stimulation
Starting date	April 2011
Contact information	Christopher Bever, MD; Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD
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