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. 2013 Jul 25;2013(7):CD006185. doi: 10.1002/14651858.CD006185.pub3

Brincks 2011

Methods Randomised cross‐over trial Method of randomisation: shuffled envelopes Blinding of outcome assessors: no Adverse events: none Deaths: none Drop‐outs: none ITT: yes
Participants Country: Denmark 13 participants (7 in treatment group, 6 in control group) All participants were ambulatory at start of study Mean age: 59 to 61 years (control and treatment groups, respectively) Inclusion criteria: unknown Exclusion criteria: unknown
Interventions 2 arms:
  • Group 1 received 3 weeks robotic‐assisted treadmill training (Lokomat), followed (after cross‐over) by 3 weeks of physiotherapy

  • Group 2 received 3 weeks of physiotherapy followed (after cross‐over) by 3 weeks of robotic‐assisted treadmill training (Lokomat)

Outcomes Outcomes were recorded at baseline, after 3 and 6 weeks later Primary outcomes: single support stance time in impaired extremity and gait asymmetry and swing time ratio Secondary outcomes: walking speed
Notes
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Shuffling envelopes
Allocation concealment (selection bias) Low risk Using sealed, shuffled envelopes
Blinding of outcome assessment (detection bias) All outcomes High risk No blinding was done
Incomplete outcome data (attrition bias) All outcomes Low risk ITT