NCT01530490

Trial name or title	Cabergoline and Hydroxyethyl Starch in Ovarian Hyperstimulation Syndrome Prevention
Methods	Randomised open, parallel trial
Participants	Women aged 18 to 40 years Inclusion criterion: women at risk of OHSS (> 20 follicles observed > 12 mm in diameter or E2 levels of 3000 pg/mL to 5000 pg/mL) Exclusion criterion: aged > 40 years
Interventions	Cabergoline group: slow infusion of 500 mL of 6% HES during follicular aspiration alone or combined with cabergoline 0.5 mg administration for 8 days, starting on the day of hCG administration Control group: slow infusion of 500 mL of 6% HES during follicular aspiration
Outcomes	Primary outcome: risk of OHSS Secondary outcome: pregnancy rate
Starting date	August 2007
Contact information	None
Notes	NCT01530490; this is the Matorras 2013 paper

3D: 3‐dimensional; β‐hCG: β‐human chorionic gonadotrophin; BMI: body mass index; COH: controlled ovarian hyperstimulation; E2: oestradiol; ET: embryo transfer; GnRH: gonadotropin‐releasing hormone; GnRHa: gonadotropin‐releasing hormone agonist; hCG: human chorionic gonadotrophin; HES: hydroxyethyl starch; hMG: human menopausal gonadotropin; ICSI: intracytoplasmic sperm injection; OHSS: ovarian hyperstimulation syndrome; RCT: randomised controlled trial.