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. 2019 Apr 1;31(3):200–206. doi: 10.1097/CCO.0000000000000515

Table 2.

Complications of focal prostate ablation

Study (references) Ablation modality Design Participants (n) Urinary tract infection rate No pad continence (6 month) Erectile dysfunction (%) Fistula rate Urinary retention rate Hematuria
Ahmed et al. 2015 [26] HIFU Prospective cohort 56 18% 96% 25% 0% 64%
Guillaumier et al. 2018 [25▪▪] HIFU Prospective cohort 625 9% 97% 40%
von Hardenberg et al. 2018 [28] HIFU Prospective cohort 24 17% 88% 20% 13% 8%
Eggener et al. 2016 [35] FLA Prospective cohort 27 0% 8% 15%
Natarajan et al. 2016 [37] FLA Prospective cohort 10 100% 0%
Lindner et al. 2009 [39] FLA Prospective cohort 12 0% 0% 0% 17%
Mendez et al. 2015 [43] Cryotherapy Prospective cohort 317 100% 31% 2% 1%
Valerio et al. 2017 [44] Cryotherapy prospective cohort 18 17% 0% 17%
Tay et al. et al. 2017 [45] Cryotherapy Propensity matched case controlled 166 95% 30% 0% 7%
Van den Bos et al. 2018 [48] IRE Prospective cohort 63 98% 23% 2%
Azzouzi et al. 2018 [50▪▪]/Gill et al. 2018 [49▪▪] PDT Prospective randomized controlled 413 21% 99% 38% 16% 28%

Key.

Unavailable data is represented by a dash (–).

FLA, focal laser ablation; HIFU, high-intensity focal ultrasound, IRE, irreversible electroporation; PDT, photodynamic therapy.