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. Author manuscript; available in PMC: 2020 Apr 15.
Published in final edited form as: Chem Res Toxicol. 2019 Feb 8;32(4):753–761. doi: 10.1021/acs.chemrestox.8b00411

Figure 3.

Figure 3.

Kinetics of appearance of NER dual incision products in HeLa cells transfected with the 32P-internally labelled DNA hairpins harboring (+)-cis-B[a]P-dG, or (+)-trans-B[a]P-dG] lesions. The NER yields were calculated by integration of the histograms derived from the denaturing gel autoradiographs at each particular incubation time (2, 4, 6 or 8 h). The results of three independent experiments and their standard deviations are shown. Other details are described in Methods.