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Loss of SETD2 increases the metabolic rate in ccRCC cells. The cell metabolic rate was measured by (A) MTT (n=3) and (B) Alamar Blue assays (n=3) at 3 hours after cell plating. (C) Cellular ATP production was measured by CellTiter-Glo reagent (n=3). (D-E) Western blot and quantitative analysis for H3K36me3 histone protein (*p<0.05).
