Figure 4.
Targeted GC-MS analysis of 786-O and isogenic SETD2-deficient 38E/38F cells. (A) PCA score plot and (B) scatter plot based on TCA cycle metabolites from 786-O, 38E, and 38F cells. (C) Quantitative analysis of aspartate, malate, succinate, fumarate, α-ketoglutarate, and lactate concentration in each cell type (n=3, *p<0.05).