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RNA-seq analysis of 786-O and isogenic SETD2-deficient 38E and 38F cells. (A) Visualization of the gene alterations between 786-O and 38E/38F cells (red indicates up-regulated genes and green indicates down-regulated genes compared to 786-O cells). (B) Gene enrichment analysis revealed the cellular biological processes affected by SETD2 inactivation. (C) Identification of disturbed gene regulation networks in SETD2-deficient 38E/38F cells.
