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. 2015 Feb 12;2015(2):CD008349. doi: 10.1002/14651858.CD008349.pub3

Crosbie 2008

Methods RCT
Participants Recruited from 2 hospital stroke units and members of Stroke Association Clubs in Northern Ireland
18 participants: 9 intervention, 9 control
Inclusion criteria: within 2 years of first stroke, medically stable, can follow 2‐stage commands, score of ≥ 25 on the upper limb Motricity Index
Exclusion criteria: mental score < 7/10, neglect (star cancellation < 48/52), comorbid conditions impacting on rehabilitation potential, cardiac pacemaker, severe arm pain reported on visual analogue scale
Mean (SD) age: intervention group 56 (15) years, control group 65 (7) years
55% male
Stroke details: 39% right hemiparesis
Timing post stroke: intervention group mean (SD) 10 (6) months, control group 12 (8) months
Interventions Virtual reality intervention: the participant chooses from a variety of activities involving reaching and grasping of virtual objects at a variety of heights, speeds and with varied number of targets; the participant wears a head‐mounted device and data glove
Control intervention: therapy provided is based on the Bobath approach
Sessions were 35 to 45 minutes, 3 times a week over 3 weeks (approximately 6 hours total)
Outcomes Outcomes recorded at baseline, post‐intervention and at 6 weeks
Upper limb function and activity outcomes: Action Research Arm Test, Upper Limb Motricity Index
Adverse events were reported
Other outcome measures: an exit questionnaire including questions about enjoyment and perception of improvement
Notes
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk An independent colleague generated the sequence using a computer random number generator
Allocation concealment (selection bias) Low risk Group allocation cards were concealed in sealed, opaque envelopes
Blinding of outcome assessment (detection bias) All outcomes Low risk Masked to allocation
Incomplete outcome data (attrition bias) All outcomes Low risk An intention‐to treat analysis was completed. Missing data points were dealt with using the simple mean imputation method
Selective reporting (reporting bias) Low risk No other outcomes were collected