Table 2.
Older adults (65+) n=91 | Younger adults (40–60 years of age) n=91 | p value | |
---|---|---|---|
Time from dialysis to transplant in days, median (range) | 1308 [38, 4971] | 1372 [14, 7037] | 0.83 |
Time on the waiting list in days, median [range] | 589 [0,2336] | 467 [0,4598] | 0.83 |
Ischemia & surgical times in minutes, median [range] | |||
Cold | 996 [10,2505] | 858 [32,2197] | 0.30 |
Warm | 28 [5,63] | 34 [18,60] | 0.06 |
Surgery | 234 [132, 628] | 236 [148, 439] | 0.95 |
PRA (%), median [range] | 0 [0,99] | 0 [0,100] | NS |
Induction regimen, n(%) | |||
Basiliximab | 44 (48.4) | 45 (49.5) | 0.88 |
ATG | 27 (29.7) | 31 (34.1) | 0.53 |
None† | 18 (19.8) | 15 (16.5) | 0.56 |
Ureteral stent used, n(%) | 71 (78.0) | 69 (75.8) | 0.86 |
Maintenance immunosuppression, n(%) | |||
Prednisone | 89 (97.8) | 88 (96.7) | 0.61 |
MMF | 88 (96.7) | 88 (96.7) | 1 |
Tacrolimus | 90 (98.9) | 88 (96.7) | 0.62 |
Sirolimus | 0 (0.0) | 1 (1.1) | NS |
Everolimus | 2 (2.2) | 0 (0.0) | NS |
Belatacept | 0 (0.0) | 1 (1.1) | NS |
Total length of mechanical ventilation in days, median (IQR)‡ | 0(0,0) | 0(0,0) | NS |
Any versus none n (%) | 10 (11.0) | 7(7.69) | 0.62 |
Transfusions (PRBCs) during transplant surgery, n(%) | 7 (7.69) | 9 (9.89) | 0.79 |
Length of hospital stay (days), median (IQR) | 6 (5,9) | 5 (4,8) | 0.04 |
Delayed graft function, n(%) | 24 (26.4) | 15 (16.7) | 0.15 |
Days on dialysis after transplant, median (IQR) | 9 (5, 16) | 7 (1, 11) | 0.26 |
Discharge location | |||
Home | 87(95.6) | 91(100.00) | NS |
Nursing Home | 1(1.10) | 0.0(0.00) | |
Hospice | 1(1.10) | 0.0(0.00) | |
Death during transplant admission | 2(2.20) | 0.0(0.00) |
PRA: panel reactive antibodies. ATG: Anti-thymocyte globulin. MMF: mycophenolate mofetil. PRBCs: packed red blood cells NS: not significant.
No induction immunosuppression would still involve methylprednisolone as per protocol.
Total days of mechanical ventilation during transplant admission.