Skip to main content
. Author manuscript; available in PMC: 2020 Jan 4.
Published in final edited form as: J Proteome Res. 2018 Dec 12;18(1):426–435. doi: 10.1021/acs.jproteome.8b00699

Figure 3.

Figure 3.

Evaluation of DIA-based differential expression. (A) Volcano plot showing a Welch’s t-test on proteins identified with two or more peptides, comparing CRC (n=10) and non-CRC (n=2) samples. 15 proteins significantly overexpressed in the CRC samples (q-value <0.01; Bonferroni multiple-hypothesis testing correction; red triangles) were selected for further analysis. Boxplots and paired samples are shown for: our proteomic quantification (B; median intensity); median mRNA expression levels obtained in TCGA studies (C); and IHC-based tumor expression levels in the Human Protein Atlas (D).