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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Crit Care Med. 2019 May;47(5):651–658. doi: 10.1097/CCM.0000000000003681

Figure 3.

Figure 3.

Intensive care unit (ICU) freedom by 1 week as a function of PBMC gene expression on Days 1, 3, and 5. Closed grey circles depict individual subjects with sepsis that were discharged from the ICU within 1 week. Open black circles depict individual subjects with sepsis that had prolonged ICU stays (≥ 1 week) or early death (within 1 week of presentation). Left Y-axis shows gene expression (qRT-PCR) for HMOX1, NRF1, PPARGC1A, and TFAM. Right T-axis shows qRT-PCR of mtDNA copy number. Black horizontal bars depict median values. Statistical analysis is Mann-Whitney U test. *P<0.05 denotes statistically significant comparisons. Trends (P<0.1) are depicted on the graphs.