Figure 3. Correlation of the change in multi-biomarker disease activity score with change in rheumatoid arthritis disease activity measures over time.
Forest plots demonstrating correlation of change in multi-biomarker disease activity score with change in RA disease activity measures including (A) DAS28-CRP, (B) SDAI, (C) CDAI, (D) RAPID3. Studies assessing correlation at multiple follow up points are modeled separately for meta-analysis.
*Patients followed up initially at 6 weeks, and again at 12 weeks if adequate treatment response not obtained in the BRASS and NESTED cohorts (Curtis 2012).